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This easy turkey tetrazzini recipe comes together quickly with just a few simple ingredients. A delicious way to use up leftover turkey without a lot of work!

I made this easy recipe for turkey tetrazzini last year using leftover Thanksgiving turkey, and my family absolutely loved it. It’s a creamy, cheesy baked pasta dish typically made with chicken, but you can use any protein, even shrimp!
What makes my recipe so easy is I use some shortcuts, because who wants to do a lot of cooking after a major holiday? Not me! So, while this isn’t completely made from scratch, it’s still delicious comfort food, and that’s what counts.
Why you’ll love this easy tetrazzini!

This cheesy pasta bake is a warm and comforting dinner made with simple family friendly ingredients and without a lot of effort!
There’s no white wine or mushrooms, so it’s perfect for kids and picky eaters.
I hope your family enjoys it as much as my family does!

What You Need to Make it
Here are the basics. Full amounts are listed in the printable recipe card below.
- Cooked turkey — cut or torn into smaller pieces
- Spaghetti — or linguine
- Cream of chicken soup — or cream of mushroom soup or any cream soup to form the base of the sauce
- Heavy cream — to thin the sauce. You can also use half and half or milk
- Sour cream — adds a little tang
- Cheese — a blend of Parmesan cheese and mozzarella cheese
- Spices — salt, black pepper, garlic powder, onion powder, Italian seasoning
How to Make Turkey Tetrazzini
First, boil the pasta, and stir the creamy sauce. Combine the pasta with the turkey and sauce mixture right in the casserole dish. Add cheese, and bake until hot and bubbly.




Recipe Tips
Save some of the pasta cooking water and use it to thin the sauce if needed.
I like to grease the baking dish with butter for extra flavor, but you can use non-stick spray or olive oil.

Storage
Store leftover pasta in an airtight container in your refrigerator for 3-4 days. You can freeze leftovers, but the sauce may separate when reheated.
Variations
We usually have leftover vegetables on the side, but you can add frozen peas or broccoli right to the baking dish.
Use rotisserie chicken if you don’t have enough turkey.
More Ways to Use Turkey Leftovers
Turkey stuffing casserole is a favorite! You can also make turkey noodle casserole, turkey soup or turkey sliders.

The Easiest Turkey Tetrazzini
Ingredients
- 16 oz spaghetti
- 10.5 oz can cream of chicken soup
- 1 cup heavy cream
- ½ cup sour cream
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- 1 teaspoon Italian seasoning
- ½ teaspoon sea salt
- ½ teaspoon black pepper
- 3 cups cooked turkey meat cut into smaller pieces
- 2 cups grated Parmesan cheese
- 2 cups shredded mozzarella cheese
Instructions
- Preheat oven to 350℉
- Grease a large casserole dish or 13×9 inch pan with butter or cooking spray
- Cook pasta in a large pot of salted boiling water
- In a large bowl, mix the soup, heavy cream, sour cream and spices
- Add the turkey to the prepared baking dish, and add drained pasta
- Stir in the sauce and 1 cup each of the Parm and Mozzarella
- Sprinkle remaining cheese on top, and bake in pre-heated oven for 25-30 minutes or until hot and bubbly
Video
Notes
Nutrition
Nutrition information is automatically calculated, so should only be used as an approximation.
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